Reboot Your Brain

Pinch your thumb to reboot your brain & body! Dr. Mandell reveals a simple technique to reduce stress, boost the immune system, and improve overall health. Experience the amazing benefits for yourself!


Did you know that you can use a simple technique to stimulate your brain and body? Dr. Mandell has discovered a hand reflex point on the nail bed of your thumb that directly affects the anterior pituitary gland in your brain. By stimulating this point, you can increase endorphins, which will boost your immune system and protect you against disease and infection. Everyone’s experience may be slightly different, but the overall result is improved health and happiness. So why not give it a try? Pinch your thumb, follow the instructions, and see the amazing benefits for yourself!

Stress is a major factor in many diseases and can weaken your immune system. That’s why Dr. Mandell has developed two proven techniques that will help you combat stress and improve your overall well-being. By focusing on the anterior pituitary gland in the brain and the reflex areas in your hand, specifically the nail bed of your thumb, you can release endorphins that will reduce stress, improve sleep, and boost your immune system. The technique is simple, effective, and takes only minutes to perform. So take control of your health and try these techniques today!

Techniques to Reduce Stress and Boost Immune System

In today’s fast-paced world, stress has become an inevitable part of our lives. From work pressures to personal commitments, there are numerous factors that contribute to our stress levels. However, it is important to understand that prolonged or chronic stress can have a negative impact on our physical and mental well-being. It can weaken our immune system, making us more susceptible to illnesses and diseases.

The immune system plays a crucial role in protecting our body against harmful pathogens and maintaining our overall health. When stressed, our immune system becomes compromised, making it difficult for the body to fight off infections and diseases effectively. Therefore, finding effective techniques to reduce stress and boost our immune system is essential for our well-being.

In this article, we will explore two powerful techniques that can help mitigate stress levels and strengthen our immune system. These techniques primarily focus on stimulating the anterior pituitary gland and promoting the release of endorphins in our body. We will also discuss the importance of proper hand positioning and provide step-by-step instructions to practice these techniques effectively.

Understanding these techniques and incorporating them into your daily routine can significantly improve your stress management skills and enhance your overall health and well-being. So, let’s dive in and explore these techniques in detail.

Understanding the Anterior Pituitary Gland

The pituitary gland, often referred to as the “master gland,” is a small, pea-sized gland located at the base of the brain. Despite its relatively small size, the pituitary gland plays a vital role in regulating hormones throughout the body. It secretes various hormones that control and coordinate the functions of other glands and organs, including the adrenal glands.

The anterior pituitary gland, in particular, is responsible for the secretion of important hormones that affect our overall health, such as norepinephrine and cortisol. However, excessive secretion of these hormones can lead to various health problems, including increased stress, anxiety, inflammation, and weakened immune system response.

Pinch Your Thumb To Reboot Your Brain Body! Dr. Mandell

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The Effect of Endorphins on the Body

Endorphins are natural chemicals produced by the anterior pituitary gland in our brain. These chemicals act as neurotransmitters and play a crucial role in naturally relieving pain and inducing feelings of pleasure and relaxation. When endorphins are released in our body, they can have a positive impact on our overall health and well-being.

Not only do endorphins help reduce pain and improve our mood, but they also have significant effects on our immune system. Endorphins stimulate the immune system by activating white blood cells, which are responsible for protecting our body against diseases and infections. By increasing the production of endorphins, we can strengthen our immune system and improve our body’s ability to fend off illnesses.

Hand Reflex Points for Stimulating the Pituitary Gland

One effective way to stimulate the anterior pituitary gland and promote the release of endorphins is through reflexology. Reflexology is based on the concept that specific reflex areas in the hands and feet correspond to different organs and glands in the body. By applying pressure to these reflex areas, we can create therapeutic effects and promote overall well-being.

In the case of stimulating the anterior pituitary gland, the reflex area lies in the nail bed of our thumb. By applying pressure and stimulating this reflex area, we can activate the pituitary gland and initiate the release of endorphins. This, in turn, helps strengthen our immune system and reduces stress levels.

Pinch Your Thumb To Reboot Your Brain Body! Dr. Mandell

Step-by-Step Technique: Stimulating the Nail Bed

To practice this technique effectively, it is important to follow proper hand positioning and apply the right amount of pressure. Here is a step-by-step guide:

  1. Proper Hand Positioning:
    • Take your dominant hand and extend your thumb in front of you.
    • Use the first and second fingers of your other hand to grab the nail bed behind your thumb.
    • Ensure a comfortable grip and position your fingers in a way that allows you to stimulate the nail bed effectively.
  2. Applying Pressure on the Nail Bed:
    • With your first and second fingers, stimulate the nail bed by applying gentle pressure for about 15 to 20 seconds.
    • Be mindful of the amount of pressure you exert and adjust it according to your comfort level.
    • Focus on maintaining a steady and rhythmic pressure during the stimulation process.
  3. Duration of stimulation:
    • After stimulating the nail bed for 15 to 20 seconds, shift your focus to the outer sides of the nail bed.
    • Squeeze and hold that position for about 20 to 30 seconds.
    • Pay attention to any sensations or changes occurring behind your nasal area and eyes.

By regularly practicing this technique, you can experience various physiological changes that indicate the stimulation of the pituitary gland and the release of endorphins. Some common experiences include increased focus, a sense of relief or relaxation, and even a slight opening of your sinuses. These neurophysiological responses are positive signs that the technique is working effectively.

Neurophysiological Changes and Effects

During the stimulation of the anterior pituitary gland reflex area, there are specific changes and effects that occur within our body. These changes primarily manifest behind the nasal and eye areas, as well as inside the brain. Understanding and recognizing these sensations can help you gauge the effectiveness of the technique. Some key points to note include:

  1. Changes Occurring in the Nasal and Eye Area:
    • Some individuals may experience a feeling of pressure behind the nasal area.
    • Others may notice a slight change in their vision or feelings of pressure or tension around the eyes.
  2. Sensations and Reactions During Stimulation:
    • Some people may feel more focused or in-tune with their senses during the stimulation process.
    • You may even notice a slight tingling sensation in your fingers or the stimulated areas.
  3. Signs of Neurophysiological Response:
    • A common manifestation of the technique’s effectiveness is the opening or clearing of the nasal passages.
    • Some individuals may also experience a sense of calmness or relief from stress and anxiety.

These changes and sensations are normal physiological responses and indicate that the technique is working to stimulate the pituitary gland effectively. Embrace these sensations as a sign of progress toward achieving a state of balance and reduced stress levels.

Pinch Your Thumb To Reboot Your Brain Body! Dr. Mandell

Amplifying the Effect with Additional Reflex Areas

While stimulating the nail bed of the thumb is highly effective in activating the pituitary gland, you can further enhance the technique by incorporating additional reflex areas in your hands. By targeting these reflex areas, you can amplify the effects on the brain and promote overall well-being. Here are two techniques you can try:

  1. Stimulating Reflex Areas, on the other hand:
    • After practicing the technique on your dominant hand, switch to your non-dominant hand.
    • Repeat the process of stimulating the nail bed and the outer sides of the nail bed with the same duration and pressure.
    • By stimulating the reflex areas on both hands, you can enhance the overall effect on the pituitary gland.
  2. Using Thumb and Finger Techniques Simultaneously:
    • Instead of using only your fingers to stimulate the reflex areas, combine thumb and finger techniques.
    • Place your thumb on the nail bed and use your fingers to squeeze and stimulate the outer sides of the nail bed simultaneously.
    • This combination technique can provide a more comprehensive and intense stimulation, resulting in enhanced effects on the pituitary gland.

By incorporating these additional reflex areas and techniques, you can further boost the stimulation of the anterior pituitary gland and improve the overall effectiveness of the technique.

Enhanced Effects on the Autonomic Nervous System

The techniques we have discussed so far not only stimulate the pituitary gland and endorphin release but also have a profound impact on the autonomic nervous system. The autonomic nervous system consists of two main branches: the sympathetic nervous system and the parasympathetic nervous system.

The sympathetic nervous system is associated with the body’s “fight-or-flight” response, which is triggered during stressful situations. On the other hand, the parasympathetic nervous system promotes the body’s “rest-and-digest” response, facilitating relaxation and promoting overall well-being.

By practicing the techniques we have discussed, you can activate the parasympathetic nervous system and induce a state of relaxation and tranquility. This shift from the sympathetic to the parasympathetic mode helps reduce stress levels, regulate heart rate and blood pressure, and improve overall physiological balance.

Achieving Homeostasis and Reducing Stress Levels

The primary goal of practicing these techniques is to achieve homeostasis within the body. Homeostasis refers to the body’s state of balance and stability, where all systems are functioning harmoniously. By stimulating the anterior pituitary gland and releasing endorphins, we can create a state of equilibrium within our body, reducing stress levels and restoring overall well-being.

Regular practice of these techniques will not only help you manage stress effectively but also strengthen your immune system. By strengthening your immune system, you can protect yourself against diseases and infections more efficiently, leading to improved overall health and well-being.

Frequency and Benefits of Regular Practice

To reap the maximum benefits of these techniques, it is recommended to practice them regularly. Consistency is key when it comes to training your body to respond positively to the stimulation of the anterior pituitary gland and the release of endorphins. Here are a few key points regarding the frequency and benefits of regular practice:

  1. Recommended Frequency of Technique Practice:
    • Aim to practice these techniques at least once or twice daily.
    • You can incorporate them into your daily routine by setting aside a dedicated time, such as in the morning or before bedtime.
    • The more consistently you practice, the more impactful the effects will be on your overall well-being.
  2. Improvement in Stress Management and Immune System Strength:
    • Regular practice of these techniques will enable you to manage stress more effectively.
    • By reducing stress levels, you can experience improved mental clarity, better sleep quality, and enhanced mood.
  3. Overall Health Benefits:
    • Strengthened immune system: Regular practice of these techniques will improve your body’s defense mechanisms, making you less susceptible to illnesses and infections.
    • Improved emotional well-being: The release of endorphins promotes relaxation, reduces anxiety, and improves self-esteem, resulting in better emotional well-being.
    • Enhanced physical health: By managing stress levels and strengthening your immune system, you can reduce the risk of chronic diseases, such as cardiovascular disease and diabetes, and improve your overall physical health.


In conclusion, incorporating techniques to reduce stress and boost the immune system is crucial for maintaining a healthy and balanced lifestyle. By practicing the reflexology technique to stimulate the anterior pituitary gland and release endorphins, we can effectively manage stress levels and strengthen our immune system.

Remember, these techniques require consistency and commitment to experience their full impact. Practice them regularly, paying attention to the effects and sensations occurring within your body. As you continue to refine your practice, you will notice significant improvements in your stress management skills and overall well-being.

So, don’t hesitate to give these techniques a try. Share this article with your friends and family, encourage them to practice along with you, and embark on a journey towards improved well-being. As always, take care, stay healthy, and embrace the power of these techniques in your life.